Registered Nurse Salary Guide: Saint Louis, MO
Average Registered Nurse Salary
$49.47/hour
The average salary for a Registered Nurse in Saint Louis, MO is $49.47 per hour. This is 30% higher than the Missouri average of $34.63.
Last updated on December 20, 2025. Based on active jobs on Vivian.com.
Registered Nurse salaries in Saint Louis, MO compared to State and National Averages
$49.47/hour
Saint Louis, MO
20% higher than the US average.
$34.63/hour
Missouri
15% lower than the US average.
$39.69/hour
United States
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
Chesterfield, Missouri
$32/hour
This is 56% lower than the Saint Louis average of $49.47.
Florissant, Missouri
--/hour
Cape Girardeau, Missouri
$30/hour
This is 68% lower than the Saint Louis average of $49.47.
What are the highest paying Agencies for Registered Nurse jobs in Saint Louis?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Select Medical | $48 | $55 |
| BJC HealthCare | $40 | $51 |
| Elara Caring | $40 | $40 |
Last updated on December 20, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Home Health Case Management
- ChenMed
- St. Louis, MO
$73K-104K/year
Registered Nurse (RN) - Home Health
- Elara Caring
- St. Louis, MO
$34-46/hour
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